Six-minute walk test in pulmonary arterial hypertension

Association between six-minute walk distance and long-term outcomes in patients with pulmonary arterial hypertension: Data from the randomized SERAPHIN trial

BACKGROUND Patients with pulmonary arterial hypertension who achieve a six-minute walk distance of 380-440 m may have improved prognosis. Using the randomized controlled trial of macitentan in pulmonary arterial hypertension (SERAPHIN), the association between six-minute walk distance and long-term outcomes was explored. METHODS Patients with six-minute walk distance data at Month 6 were dich...

The Six-minute Walk Test (6MWT) for the Evaluation of Pulmonary Diseases

The six-minute walk test (6MWT) is a well-tolerated test which reflects daily activities and can be easily used in clinical practice. The 6MWT provides information about functional capacity, response to therapy and prognosis across a range of chronic cardiopulmonary conditions. Moreover, the 6MWT is sensitive to the common therapies used for chronic obstructive pulmonary disease, such as pulmon...

Six-minute walk test in scleroderma-associated pulmonary arterial hypertension: are we counting what counts?

Hemodynamic profile of severity at pulmonary vasoreactivity test in schistosomiasis patients.

BACKGROUND The pulmonary vasoreactivity rate of Schistosomal Pulmonary Artery Hypertension (SPAH) is not known. Hemodynamic data obtained by cardiac catheterization are associated with the most commonly used clinical criteria of severity. OBJECTIVE To estimate the percentage of positive vasoreactivity to nitric oxide in schistosomal pulmonary arterial hypertension and verify the association o...

Benefits from the correction of vitamin D deficiency in patients with pulmonary hypertension

Background: Vitamin D (Vit D) is linked to various conditions including musculoskeletal, metabolic and   cardiopulmonary diseases. However, it is not clear whether correction of vit D deficiency exerts any beneficial effect in patients with pulmonary hypertension. Methods: This study was a prospective uncontrolled longitudinal study. Patients with pulmonary hypertension and vit D d...

Oxygen desaturation on the six-minute walk test and mortality in untreated primary pulmonary hypertension.

There are no reliable predictors of mortality in primary pulmonary hypertension (PPH). This study assessed whether exercise oxygen desaturation and distance achieved during a six-minute walk are associated with mortality in moderately symptomatic patients with PPH. Thirty-four patients with PPH underwent a pretreatment six-minute walk test, and an invasive haemodynamic assessment of pulmonary v...